Novo Nordisk revealed impressive results from two Phase 3 trials for its obesity and diabetes treatment, CagriSema, at the American Diabetes Association’s annual meeting in Chicago. Over 68 weeks, participants experienced up to 23% weight loss in obese individuals and 16% in overweight adults with type 2 diabetes. Alongside weight loss, the drug showed promising improvements in blood sugar control.

Key Findings:

• Glycated hemoglobin levels of ≤6.5%: Achieved by 73.5% of participants on CagriSema compared to 15.9% on placebo.

• Gastrointestinal side effects: Reported by 79.6% of patients on CagriSema, mostly mild.

• Severe adverse reactions: Occurred in 9.8% of the CagriSema group, against 6.1% in the placebo group.

• Discontinuation due to side effects: 6% for CagriSema versus 3.7% in the placebo group.

Despite prior investor concerns following the topline results, these detailed findings may restore confidence in the drug’s potential benefits for metabolic health and its regulatory prospects.

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